MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension

Loss of the growth-suppressive effects of bone morphogenetic protein (BMP) signaling has been demonstrated to promote pulmonary arterial endothelial cell dysfunction and induce pulmonary arterial smooth muscle cell (PASMC) proliferation, leading to the development of pulmonary arterial hypertension...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Rothman, Alexander M.K., Arnold, Nadine D., Pickworth, Josephine A., Iremonger, James, Ciuclan, Loredana, Allen, Robert M.H., Guth-Gundel, Sabine, Southwood, Mark, Morrell, Nicholas W., Thomas, Matthew, Francis, Sheila E., Rowlands, David J., Lawrie, Allan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922709/
https://ncbi.nlm.nih.gov/pubmed/27214554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83361
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