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Inhibition of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by the progressive narrowing and occlusion of small pulmonary arteries. Current therapies fail to fully reverse this vascular remodeling. Identifying key pathways in disease pathogenesis is therefore required for the d...

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Detalhes bibliográficos
Main Authors: Hameed, Abdul G., Arnold, Nadine D., Chamberlain, Janet, Pickworth, Josephine A., Paiva, Claudia, Dawson, Sarah, Cross, Simon, Long, Lu, Zhao, Lan, Morrell, Nicholas W., Crossman, David C., Newman, Christopher M.H., Kiely, David G., Francis, Sheila E., Lawrie, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478928/
https://ncbi.nlm.nih.gov/pubmed/23071256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112716
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