Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

BACKGROUND: The death receptor ligand tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) shows considerable clinical promise as a therapeutic agent. TRAIL induces leukocyte apoptosis, reducing acute inflammatory responses in the lung. It is not known whether TRAIL modifies chronic lung...

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Detalhes bibliográficos
Main Authors: McGrath, Emmet E, Lawrie, Allan, Marriott, Helen M, Mercer, Paul, Cross, Simon S, Arnold, Nadine, Singleton, Vanessa, Thompson, Alfred A R, Walmsley, Sarah R, Renshaw, Stephen A, Sabroe, Ian, Chambers, Rachel C, Dockrell, David H, Whyte, Moira K B
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2012
Assuntos:
Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426075/
https://ncbi.nlm.nih.gov/pubmed/22496351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2011-200863
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