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Chimeric antigen receptor-modified T cells strike back
Chimeric antigen receptors (CARs) are engineered molecules designed to endow a polyclonal T-cell population with the ability to recognize tumor-associated surface antigens. In their simplest form, CARs comprise a targeting moiety in the form of a single-chain variable fragment from an antibody conne...
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| Publié dans: | Int Immunol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922025/ https://ncbi.nlm.nih.gov/pubmed/27021308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw018 |
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