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Making Better Chimeric Antigen Receptors for Adoptive T-cell Therapy

Chimeric antigen receptors (CARs) are engineered fusion proteins constructed from antigen recognition, signaling, and costimulatory domains that can be expressed in cytotoxic T cells with the purpose of reprograming the T cells to specifically target tumor cells. CAR T-cell therapy uses gene transfe...

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Bibliografski detalji
Izdano u:Clin Cancer Res
Glavni autori: Maus, Marcela V., June, Carl H.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843171/
https://ncbi.nlm.nih.gov/pubmed/27084741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1433
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