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Chimeric antigen receptor-modified T cells strike back

Chimeric antigen receptors (CARs) are engineered molecules designed to endow a polyclonal T-cell population with the ability to recognize tumor-associated surface antigens. In their simplest form, CARs comprise a targeting moiety in the form of a single-chain variable fragment from an antibody conne...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Frigault, Matthew J., Maus, Marcela V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922025/
https://ncbi.nlm.nih.gov/pubmed/27021308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw018
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