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Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy
The genetic modification and characterization of T-cells with chimeric antigen receptors (CARs) allow functionally distinct T-cell subsets to recognize specific tumor cells. The incorporation of costimulatory molecules or cytokines can enable engineered T-cells to eliminate tumor cells. CARs are gen...
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| Publicado en: | J Natl Cancer Inst |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4948566/ https://ncbi.nlm.nih.gov/pubmed/26819347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv439 |
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