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Current status and perspectives of chimeric antigen receptor modified T cells for cancer treatment

Chimeric antigen receptor (CAR) is a recombinant immunoreceptor combining an antibody-derived targeting fragment with signaling domains capable of activating cells, which endows T cells with the ability to recognize tumor-associated surface antigens independent of the expression of major histocompat...

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Bibliografski detalji
Izdano u:Protein Cell
Glavni autori: Wang, Zhenguang, Guo, Yelei, Han, Weidong
Format: Artigo
Jezik:Inglês
Izdano: Higher Education Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712290/
https://ncbi.nlm.nih.gov/pubmed/28466386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0400-z
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