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Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms

Multiple isoforms of aggregation-prone proteins are present under physiological conditions and have the propensity to assemble into co-oligomers with different properties from self-oligomers, but this process has not been quantitatively studied to date. We have investigated the amyloid-β (Aβ) peptid...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Iljina, Marija, Garcia, Gonzalo A., Dear, Alexander J., Flint, Jennie, Narayan, Priyanka, Michaels, Thomas C. T., Dobson, Christopher M., Frenkel, Daan, Knowles, Tuomas P. J., Klenerman, David
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921824/
https://ncbi.nlm.nih.gov/pubmed/27346247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28658
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