Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

Clathrin-coated vesicles form by rapid assembly of discrete coat constituents into a cargo-sorting lattice. How the sequential phases of coat construction are choreographed is unclear, but transient protein-protein interactions mediated by short interaction motifs are pivotal. We show that arrayed A...

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Foilsithe in:Dev Cell
Main Authors: Ma, Li, Umasankar, Perunthottathu K., Wrobel, Antoni G., Lymar, Anastasia, McCoy, Airlie J., Holkar, Sachin S., Jha, Anupma, Pradhan-Sundd, Tirthadipa, Watkins, Simon C., Owen, David J., Traub, Linton M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921775/
https://ncbi.nlm.nih.gov/pubmed/27237791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.05.003
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