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A Phosphotyrosine Switch for Cargo Sequestration at Clathrin-coated Buds

The AP-2 clathrin adaptor complex oversees endocytic cargo selection in two parallel but independent manners. First, by physically engaging peptide-based endocytic sorting signals, a subset of clathrin-dependent transmembrane cargo is directly collected into assembling buds. Synchronously, by intera...

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Detalhes bibliográficos
Main Authors: Chakraborty, Souvik, Umasankar, Perunthottathu K., Preston, G. Michael, Khandelwal, Puneet, Apodaca, Gerard, Watkins, Simon C., Traub, Linton M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067187/
https://ncbi.nlm.nih.gov/pubmed/24798335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556589
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