Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

Clathrin-coated vesicles form by rapid assembly of discrete coat constituents into a cargo-sorting lattice. How the sequential phases of coat construction are choreographed is unclear, but transient protein-protein interactions mediated by short interaction motifs are pivotal. We show that arrayed A...

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Udgivet i:Dev Cell
Main Authors: Ma, Li, Umasankar, Perunthottathu K., Wrobel, Antoni G., Lymar, Anastasia, McCoy, Airlie J., Holkar, Sachin S., Jha, Anupma, Pradhan-Sundd, Tirthadipa, Watkins, Simon C., Owen, David J., Traub, Linton M.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921775/
https://ncbi.nlm.nih.gov/pubmed/27237791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.05.003
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