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Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

RNA molecules adopt a wide variety of structures that perform many cellular functions, including, among others, catalysis, small molecule sensing, and cellular defense. Our ability to characterize, predict, and design RNA structures are key factors for understanding and controlling the biological ro...

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Bibliografiske detaljer
Udgivet i:Methods
Main Authors: Watters, Kyle E., Yu, Angela M, Strobel, Eric J., Settle, Alex H., Lucks, Julius B.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921265/
https://ncbi.nlm.nih.gov/pubmed/27064082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.04.002
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