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Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq

Many non-coding RNAs form structures that interact with cellular machinery to control gene expression. A central goal of molecular and synthetic biology is to uncover design principles linking RNA structure to function to understand and engineer this relationship. Here we report a simple, high-throu...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Watters, Kyle E., Abbott, Timothy R., Lucks, Julius B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737173/
https://ncbi.nlm.nih.gov/pubmed/26350218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv879
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