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Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

RNA molecules adopt a wide variety of structures that perform many cellular functions, including, among others, catalysis, small molecule sensing, and cellular defense. Our ability to characterize, predict, and design RNA structures are key factors for understanding and controlling the biological ro...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Watters, Kyle E., Yu, Angela M, Strobel, Eric J., Settle, Alex H., Lucks, Julius B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921265/
https://ncbi.nlm.nih.gov/pubmed/27064082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.04.002
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