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Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

RNA molecules adopt a wide variety of structures that perform many cellular functions, including, among others, catalysis, small molecule sensing, and cellular defense. Our ability to characterize, predict, and design RNA structures are key factors for understanding and controlling the biological ro...

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Библиографические подробности
Опубликовано в: :Methods
Главные авторы: Watters, Kyle E., Yu, Angela M, Strobel, Eric J., Settle, Alex H., Lucks, Julius B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921265/
https://ncbi.nlm.nih.gov/pubmed/27064082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.04.002
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