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Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

RNA molecules adopt a wide variety of structures that perform many cellular functions, including, among others, catalysis, small molecule sensing, and cellular defense. Our ability to characterize, predict, and design RNA structures are key factors for understanding and controlling the biological ro...

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Vydáno v:Methods
Hlavní autoři: Watters, Kyle E., Yu, Angela M, Strobel, Eric J., Settle, Alex H., Lucks, Julius B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921265/
https://ncbi.nlm.nih.gov/pubmed/27064082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.04.002
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