Characterizing RNA structures in vitro and in vivo with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

RNA molecules adopt a wide variety of structures that perform many cellular functions, including, among others, catalysis, small molecule sensing, and cellular defense. Our ability to characterize, predict, and design RNA structures are key factors for understanding and controlling the biological ro...

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Bibliographic Details
Published in:Methods
Main Authors: Watters, Kyle E., Yu, Angela M, Strobel, Eric J., Settle, Alex H., Lucks, Julius B.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921265/
https://ncbi.nlm.nih.gov/pubmed/27064082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.04.002
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