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Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea
Loss of sensory hair cells of the inner ear due to aminoglycoside exposure is a major cause of hearing loss. Using an immortalized multipotent otic progenitor (iMOP) cell line, specific signaling pathways that promote otic cell survival were identified. Of the signaling pathways identified, the PI3K...
Shranjeno v:
| izdano v: | Biol Open |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Company of Biologists Ltd
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4920183/ https://ncbi.nlm.nih.gov/pubmed/27142333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.016758 |
| Oznake: |
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