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Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea

Loss of sensory hair cells of the inner ear due to aminoglycoside exposure is a major cause of hearing loss. Using an immortalized multipotent otic progenitor (iMOP) cell line, specific signaling pathways that promote otic cell survival were identified. Of the signaling pathways identified, the PI3K...

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Bibliografski detalji
Izdano u:Biol Open
Glavni autori: Jadali, Azadeh, Kwan, Kelvin Y.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920183/
https://ncbi.nlm.nih.gov/pubmed/27142333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.016758
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