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Activation of CHK1 in Supporting Cells Indirectly Promotes Hair Cell Survival
The sensory hair cells of the inner ear are exquisitely sensitive to ototoxic insults. Loss of hair cells after exposure to ototoxic agents causes hearing loss. Chemotherapeutic agents such as cisplatin causes hair cell loss. Cisplatin forms DNA mono-adducts as well as intra- and inter-strand DNA cr...
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| Publicado no: | Front Cell Neurosci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435747/ https://ncbi.nlm.nih.gov/pubmed/28572758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00137 |
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