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Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea

Post-translational modification of histones is an important form of chromatin regulation impacting transcriptional activation. Histone acetyltransferases (HATs), for example, acetylate lysine residues on histone tails enhancing gene transcription, while histone deacetylases (HDACs) remove those acet...

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Bibliographic Details
Main Authors: Chen, Fu-Quan, Schacht, Jochen, Sha, Su-Hua
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341988/
https://ncbi.nlm.nih.gov/pubmed/19141081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05871.x
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