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PTEN attenuates PIP(3)/Akt signaling in the cochlea of the aging CBA/J mouse

We have previously reported the activation of cell death pathways in the sensory cells of the aging cochlea. Here we investigate age-associated changes in survival mechanisms focusing on phosphatidylinositol 3,4,5-trisphosphate (PIP(3))/Akt signaling. The animal model is the CBA/J mouse of 18 months...

詳細記述

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書誌詳細
主要な著者: Sha, Su-Hua, Chen, Fu-Quan, Schacht, Jochen
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868099/
https://ncbi.nlm.nih.gov/pubmed/19761823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2009.09.002
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