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PTEN attenuates PIP(3)/Akt signaling in the cochlea of the aging CBA/J mouse
We have previously reported the activation of cell death pathways in the sensory cells of the aging cochlea. Here we investigate age-associated changes in survival mechanisms focusing on phosphatidylinositol 3,4,5-trisphosphate (PIP(3))/Akt signaling. The animal model is the CBA/J mouse of 18 months...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868099/ https://ncbi.nlm.nih.gov/pubmed/19761823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2009.09.002 |
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