Mendelian Randomisation study of the influence of eGFR on coronary heart disease

Impaired kidney function, as measured by reduced estimated glomerular filtration rate (eGFR), has been associated with increased risk of coronary heart disease (CHD) in observational studies, but it is unclear whether this association is causal or the result of confounding or reverse causation. In t...

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Udgivet i:Sci Rep
Main Authors: Charoen, Pimphen, Nitsch, Dorothea, Engmann, Jorgen, Shah, Tina, White, Jonathan, Zabaneh, Delilah, Jefferis, Barbara, Wannamethee, Goya, Whincup, Peter, Mulick Cassidy, Amy, Gaunt, Tom, Day, Ian, McLachlan, Stela, Price, Jacqueline, Kumari, Meena, Kivimaki, Mika, Brunner, Eric, Langenberg, Claudia, Ben-Shlomo, Yoav, Hingorani, Aroon, Whittaker, John, Pablo Casas, Juan, Dudbridge, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919785/
https://ncbi.nlm.nih.gov/pubmed/27338949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28514
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