Marginal role for 53 common genetic variants in cardiovascular disease prediction

OBJECTIVE: We investigated discrimination and calibration of cardiovascular disease (CVD) risk scores when genotypic was added to phenotypic information. The potential of genetic information for those at intermediate risk by a phenotype-based risk score was assessed. METHODS: Data were from seven pr...

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Detalhes bibliográficos
Publicado no:Heart
Main Authors: Morris, Richard W, Cooper, Jackie A, Shah, Tina, Wong, Andrew, Drenos, Fotios, Engmann, Jorgen, McLachlan, Stela, Jefferis, Barbara, Dale, Caroline, Hardy, Rebecca, Kuh, Diana, Ben-Shlomo, Yoav, Wannamethee, S Goya, Whincup, Peter H, Casas, Juan-Pablo, Kivimaki, Mika, Kumari, Meena, Talmud, Philippa J, Price, Jacqueline F, Dudbridge, Frank, Hingorani, Aroon D, Humphries, Steve E
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Cardiac Risk Factors and Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099215/
https://ncbi.nlm.nih.gov/pubmed/27365493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2016-309298
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