Sixty-Five Common Genetic Variants and Prediction of Type 2 Diabetes

We developed a 65 type 2 diabetes (T2D) variant–weighted gene score to examine the impact on T2D risk assessment in a U.K.-based consortium of prospective studies, with subjects initially free from T2D (N = 13,294; 37.3% women; mean age 58.5 [38–99] years). We compared the performance of the gene sc...

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Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Talmud, Philippa J., Cooper, Jackie A., Morris, Richard W., Dudbridge, Frank, Shah, Tina, Engmann, Jorgen, Dale, Caroline, White, Jon, McLachlan, Stela, Zabaneh, Delilah, Wong, Andrew, Ong, Ken K., Gaunt, Tom, Holmes, Michael V., Lawlor, Debbie A., Richards, Marcus, Hardy, Rebecca, Kuh, Diana, Wareham, Nicholas, Langenberg, Claudia, Ben-Shlomo, Yoav, Wannamethee, S. Goya, Strachan, Mark W.J., Kumari, Meena, Whittaker, John C., Drenos, Fotios, Kivimaki, Mika, Hingorani, Aroon D., Price, Jacqueline F., Humphries, Steve E.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2015
Teme:
Genetics/Genomes/Proteomics/Metabolomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407866/
https://ncbi.nlm.nih.gov/pubmed/25475436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1504
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