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Mendelian Randomisation study of the influence of eGFR on coronary heart disease

Impaired kidney function, as measured by reduced estimated glomerular filtration rate (eGFR), has been associated with increased risk of coronary heart disease (CHD) in observational studies, but it is unclear whether this association is causal or the result of confounding or reverse causation. In t...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Charoen, Pimphen, Nitsch, Dorothea, Engmann, Jorgen, Shah, Tina, White, Jonathan, Zabaneh, Delilah, Jefferis, Barbara, Wannamethee, Goya, Whincup, Peter, Mulick Cassidy, Amy, Gaunt, Tom, Day, Ian, McLachlan, Stela, Price, Jacqueline, Kumari, Meena, Kivimaki, Mika, Brunner, Eric, Langenberg, Claudia, Ben-Shlomo, Yoav, Hingorani, Aroon, Whittaker, John, Pablo Casas, Juan, Dudbridge, Frank
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919785/
https://ncbi.nlm.nih.gov/pubmed/27338949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28514
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