LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV

Persistence of latent, replication-competent Human Immunodeficiency Virus type 1 (HIV-1) provirus is the main impediment towards a cure for HIV/AIDS (Acquired Immune Deficiency Syndrome). Therefore, different therapeutic strategies to eliminate the viral reservoirs are currently being explored. We h...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Vranckx, Lenard S., Demeulemeester, Jonas, Saleh, Suha, Boll, Annegret, Vansant, Gerlinde, Schrijvers, Rik, Weydert, Caroline, Battivelli, Emilie, Verdin, Eric, Cereseto, Anna, Christ, Frauke, Gijsbers, Rik, Debyser, Zeger
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919729/
https://ncbi.nlm.nih.gov/pubmed/27428435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.04.039
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