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Dual Roles of O-Glucose Glycans Redundant with Monosaccharide O-Fucose on Notch in Notch Trafficking

Notch is a transmembrane receptor that mediates cell-cell interactions and controls various cell-fate specifications in metazoans. The extracellular domain of Notch contains multiple epidermal growth factor (EGF)-like repeats. At least five different glycans are found in distinct sites within these...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Matsumoto, Kenjiroo, Ayukawa, Tomonori, Ishio, Akira, Sasamura, Takeshi, Yamakawa, Tomoko, Matsuno, Kenji
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919456/
https://ncbi.nlm.nih.gov/pubmed/27129198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710483
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