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Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft Recipients

The ability of regulatory T cells (Treg) to prolong allograft survival and promote transplant tolerance in lymphodepleted rodents is well-established. Very few studies, however, have addressed the therapeutic potential of adoptively-transferred, CD4(+)CD25(+)CD127(−)Foxp3(+) (Treg) in clinically-rel...

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Dettagli Bibliografici
Pubblicato in:Am J Transplant
Autori principali: Ezzelarab, M. B., Zhang, H., Guo, H., Lu, L., Zahorchak, A. F., Wiseman, R. W., Nalesnik, M. A., Bhama, J. K., Cooper, D. K. C., Thomson, A. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919255/
https://ncbi.nlm.nih.gov/pubmed/26700196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13685
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