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Sequential monitoring and stability of ex vivo-expanded autologous and non-autologous regulatory T cells following infusion in non-human primates
Ex vivo-expanded cynomolgus monkey CD4(+)CD25(+)CD127(−) regulatory T cells (Treg) maintained Foxp3 demethylation status at the Treg-Specific Demethylation Region (TSDR), and potently suppressed T cell proliferation through 3 rounds of expansion. When CFSE- or VPD450-labeled autologous (auto) and no...
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| Publicado no: | Am J Transplant |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4773915/ https://ncbi.nlm.nih.gov/pubmed/25783759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13113 |
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