Ex vivo-expanded cynomolgus macaque regulatory T cells are resistant to alemtuzumab-mediated cytotoxicity

Alemtuzumab (Campath-1H) is a humanized monoclonal antibody (Ab) directed against CD52 that depletes lymphocytes and other leukocytes, mainly by complement-dependent mechanisms. We investigated the influence of alemtuzumab (i) on ex vivo-expanded cynomolgus monkeys regulatory T cells (Treg) generate...

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Detaylı Bibliyografya
Asıl Yazarlar: Dons, E.M., Raimondi, G., Zhang, H., Zahorchak, A.F., Bhama, J.K., Lu, L., Ezzelarab, M., Ijzermans, J.N.M., Cooper, D.K.C., Thomson, A.W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780590/
https://ncbi.nlm.nih.gov/pubmed/23635093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12248
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