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Impact of Human Mutant TGFβ1/Fc Protein on Memory and Regulatory T Cell Homeostasis Following Lymphodepletion in Nonhuman Primates
Transforming growth factor β1 (TGFβ1) plays a key role in T cell homeostasis and peripheral tolerance. We evaluated the influence of a novel human mutant TGFβ1/Fc protein on memory CD4(+) and CD8(+) Tcell (Tmem) responses in vitro and their recovery following anti-thymocyte globulin (ATG)-mediated l...
Shranjeno v:
| izdano v: | Am J Transplant |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5121100/ https://ncbi.nlm.nih.gov/pubmed/27217298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13883 |
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