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BMP Signaling is Required for Aortic Valve Calcification

OBJECTIVE: Calcific Aortic Valve Disease (CAVD) is the most prevalent type of heart valve disease, affecting ~2% of the US population. CAVD is characterized by the presence of calcific nodules resulting in aortic valve (AoV) stenosis; however, the underlying mechanisms driving disease remain unknown...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Gomez-Stallons, M. Victoria, Wirrig-Schwendeman, Elaine E., Hassel, Keira R., Conway, Simon J., Yutzey, Katherine E.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919184/
https://ncbi.nlm.nih.gov/pubmed/27199449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307526
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