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Conserved transcriptional regulatory mechanisms in aortic valve development and disease

There is increasing evidence for activation of developmental transcriptional regulatory pathways in heart valve disease. Here we review molecular regulatory mechanisms involved in heart valve progenitor development, leaflet morphogenesis, and extracellular matrix organization that also are active in...

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Detalhes bibliográficos
Main Authors: Wirrig, Elaine E., Yutzey, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967128/
https://ncbi.nlm.nih.gov/pubmed/24665126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302071
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