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COX2 Inhibition Reduces Aortic Valve Calcification In Vivo

OBJECTIVE: Calcific aortic valve disease (CAVD) is a significant cause of morbidity and mortality, which affects approximately 1% of the US population and is characterized by calcific nodule formation and stenosis of the valve. Klotho-deficient mice were used to study the molecular mechanisms of CAV...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Wirrig, Elaine E., Gomez, M. Victoria, Hinton, Robert B., Yutzey, Katherine E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979542/
https://ncbi.nlm.nih.gov/pubmed/25722432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.305159
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