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Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease

Studies of human diseased aortic valves have demonstrated increased expression of genetic markers of valve progenitors and osteogenic differentiation associated with pathogenesis. Three potential mouse models of valve disease were examined for cellular pathology, morphology, and induction of valvulo...

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Detalhes bibliográficos
Main Authors: Cheek, Jonathan D., Wirrig, Elaine E., Alfieri, Christina M., James, Jeanne F., Yutzey, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294059/
https://ncbi.nlm.nih.gov/pubmed/22248532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.12.013
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