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Loss of β-catenin promotes chondrogenic differentiation of aortic valve interstitial cells

OBJECTIVE: The Wnt/β-catenin signaling pathway has been implicated in human heart valve disease and is required for early heart valve formation in mouse and zebrafish. However, the specific functions of Wnt/β-catenin signaling activity in heart valve maturation and maintenance in adults have not bee...

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Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Fang, Ming, Alfieri, Christina M., Hulin, Alexia, Conway, Simon J., Yutzey, Katherine E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239156/
https://ncbi.nlm.nih.gov/pubmed/25341799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304579
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