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Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease
AIMS: Myxomatous valve disease (MVD) is the most common aetiology of primary mitral regurgitation. Recent studies suggest that defects in heart valve development can lead to heart valve disease in adults. Wnt/β-catenin signalling is active during heart valve development and has been reported in huma...
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| Publicado no: | Cardiovasc Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5220675/ https://ncbi.nlm.nih.gov/pubmed/28069701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw229 |
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