Deficiency of circulating monocytes ameliorates the progression of myxomatous valve degeneration in Marfan syndrome

BACKGROUND: Myxomatous valve degeneration (MVD) involves the progressive thickening and degeneration of the heart valves, leading to valve prolapse, regurgitant blood flow, and impaired cardiac function. Leukocytes comprised primarily of macrophages have recently been detected in myxomatous valves,...

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Bibliografske podrobnosti
izdano v:Circulation
Main Authors: Kim, Andrew J., Xu, Na, Umeyama, Kazuhiro, Hulin, Alexia, Ponny, Sithara Raju, Vagnozzi, Ronald J., Green, Ellis A., Hanson, Paul, McManus, Bruce M., Nagashima, Hiroshi, Yutzey, Katherine E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017394/
https://ncbi.nlm.nih.gov/pubmed/31928435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042391
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