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Deficiency of circulating monocytes ameliorates the progression of myxomatous valve degeneration in Marfan syndrome

BACKGROUND: Myxomatous valve degeneration (MVD) involves the progressive thickening and degeneration of the heart valves, leading to valve prolapse, regurgitant blood flow, and impaired cardiac function. Leukocytes comprised primarily of macrophages have recently been detected in myxomatous valves,...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Kim, Andrew J., Xu, Na, Umeyama, Kazuhiro, Hulin, Alexia, Ponny, Sithara Raju, Vagnozzi, Ronald J., Green, Ellis A., Hanson, Paul, McManus, Bruce M., Nagashima, Hiroshi, Yutzey, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017394/
https://ncbi.nlm.nih.gov/pubmed/31928435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042391
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