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Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice
Cardiac fibrosis is characterized by excessive extracellular matrix deposition that contributes to compromised cardiac function and potentially heart failure. Cardiac pressure overload resulting from trans-aortic constriction in mice leads to cardiac fibrosis and increased Wnt/β-catenin signaling in...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5620049/ https://ncbi.nlm.nih.gov/pubmed/28959037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00840-w |
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