Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload

INTRODUCTION: The heart undergoes myocardial remodeling during progression to heart failure following pressure overload. Myocardial remodeling is associated with structural and functional changes in cardiac myocytes, fibroblasts, and the extracellular matrix (ECM) and is accompanied by inflammation....

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Detalhes bibliográficos
Publicado no:Cardiology
Main Authors: Mohammadzadeh, Naiyereh, Melleby, Arne Olav, Palmero, Sheryl, Sjaastad, Ivar, Chakravarti, Shukti, Engebretsen, Kristin V.T., Christensen, Geir, Lunde, Ida G., Tønnessen, Theis
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672712/
https://ncbi.nlm.nih.gov/pubmed/31968347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000505318
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