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Kinetic Studies and Bioactivity of Potential Manzamine Prodrugs
The manzamines represent a class of marine natural products that show considerable promise in the control of malaria but generate GI distress in rodents when administered orally in high doses. In an effort to generate manzamine prodrugs with improved antimalarial activity and reduced GI toxicity, we...
Gardado en:
| Publicado en: | J Nat Prod |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918903/ https://ncbi.nlm.nih.gov/pubmed/18598080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np800163u |
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