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Kinetic Studies and Bioactivity of Potential Manzamine Prodrugs
The manzamines represent a class of marine natural products that show considerable promise in the control of malaria but generate GI distress in rodents when administered orally in high doses. In an effort to generate manzamine prodrugs with improved antimalarial activity and reduced GI toxicity, we...
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| Publicado no: | J Nat Prod |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918903/ https://ncbi.nlm.nih.gov/pubmed/18598080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np800163u |
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