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Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm

Upf2 protein predominantly localizes to the cytoplasmic fraction, and binds to the exon junction complex (EJC) on spliced mRNA. The present study aimed to determine the cellular site where the interaction between Upf2 and EJC occurs. First, the cell lysate was fractionated into the cytoplasm and nuc...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: TATSUNO, TAKANORI, NAKAMURA, YUKA, MA, SHAOFU, TOMOSUGI, NAOHISA, ISHIGAKI, YASUHITO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918542/
https://ncbi.nlm.nih.gov/pubmed/27221324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5331
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