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Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm

Upf2 protein predominantly localizes to the cytoplasmic fraction, and binds to the exon junction complex (EJC) on spliced mRNA. The present study aimed to determine the cellular site where the interaction between Upf2 and EJC occurs. First, the cell lysate was fractionated into the cytoplasm and nuc...

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Publicat a:Mol Med Rep
Autors principals: TATSUNO, TAKANORI, NAKAMURA, YUKA, MA, SHAOFU, TOMOSUGI, NAOHISA, ISHIGAKI, YASUHITO
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918542/
https://ncbi.nlm.nih.gov/pubmed/27221324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5331
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