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Modified Ames test using a strain expressing human sulfotransferase 1C2 to assess the mutagenicity of methyleugenol

INTRODUCTION: Several alkenylbenzenes, including methyleugenol (ME), are present in a wide range of botanicals and exhibit carcinogenic and mutagenic properties. Negative results are generally obtained for alkenylbenzenes in standard in vitro genotoxicity tests, including the Ames test. A lack of mu...

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Détails bibliographiques
Publié dans:Genes Environ
Auteurs principaux: Honda, Hiroshi, Minegawa, Kazuyuki, Fujita, Yurika, Yamaguchi, Noriko, Oguma, Yoshihiro, Glatt, Hansruedi, Nishiyama, Naohiro, Kasamatsu, Toshio
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918123/
https://ncbi.nlm.nih.gov/pubmed/27350821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-016-0028-x
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