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Sulfotransferase-mediated chlorination of 1-hydroxymethylpyrene to a mutagen capable of penetrating indicator cells.

Methylated polycyclic aromatic hydrocarbons are common in the human environment. Many of them are stronger carcinogens than their purely aromatic congeners. They may be metabolized to benzylic alcohols. We report here on biochemical and toxicological characteristics of 1-hydroxymethylpyrene (HMP), a...

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Auteurs principaux: Glatt, H, Henschler, R, Phillips, D H, Blake, J W, Steinberg, P, Seidel, A, Oesch, F
Format: Artigo
Langue:Inglês
Publié: 1990
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568025/
https://ncbi.nlm.nih.gov/pubmed/2272332
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