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Necessity for retrospective evaluation of past-positive chemicals in in vitro chromosomal aberration tests using recommended cytotoxicity indices

We have demonstrated that retrospective evaluation of existing data of in vitro chromosomal aberration test using the new cytotoxicity indices RICC (relative increase in cell count) or RPD (relative population doubling) reduces the false-positive rate. We have constructed an algorithm to predict the...

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Detaylı Bibliyografya
Yayımlandı:Genes Environ
Asıl Yazarlar: Honda, Hiroshi, Fujita, Yurika, Kasamatsu, Toshio, Fuchs, Anne, Fautz, Rolf, Morita, Osamu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761126/
https://ncbi.nlm.nih.gov/pubmed/29339977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-017-0091-y
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