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Pharmacokinetics and pharmacodynamics of multiple doses of BG00010, a neurotrophic factor with anti‐hyperalgesic effects, in patients with sciatica
AIMS: BG00010 is a protein in the glial cell line‐derived neurotrophic factor (GDNF) family. It is a selective ligand for the GDNF family receptor alpha‐3 (GFRα3) co‐receptor that normalizes cellular changes resulting from damage or disease, and potentially alleviates neuropathic pain. The main obje...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917813/ https://ncbi.nlm.nih.gov/pubmed/27016000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12941 |
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