praja2 regulates KSR1 stability and mitogenic signaling

The kinase suppressor of Ras 1 (KSR1) has a fundamental role in mitogenic signaling by scaffolding components of the Ras/MAP kinase pathway. In response to Ras activation, KSR1 assembles a tripartite kinase complex that optimally transfers signals generated at the cell membrane to activate ERK. We d...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Rinaldi, L, Delle Donne, R, Sepe, M, Porpora, M, Garbi, C, Chiuso, F, Gallo, A, Parisi, S, Russo, L, Bachmann, V, Huber, R G, Stefan, E, Russo, T, Feliciello, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917648/
https://ncbi.nlm.nih.gov/pubmed/27195677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.109
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